The Neon Blue Goby should be housed in a 10 gallon or larger aquarium. Rarely will it become aggressive towards other fish. However, the Neon Blue Goby is territorial and will demonstrate aggression towards its own kind unless they are a mated pair. It is common for the Neon Blue Goby to spawn in an aquarium, laying its eggs in a crevice or empty shell.
In the wild, parasites picked off larger reef fish make up a portion of the Neon Blue Goby's natural diet. However, in the home aquarium, the Neon Blue Goby needs to be fed a variety of live and frozen brine shrimp, frozen mysis shrimp, table shrimp, and frozen food preparations for carnivores. If kept in a reef aquarium, the Neon Blue Goby should be fed once per day.
Source: Live Aquaria.